The microbiome and the role of postbiotics in FREEZE VITAMINS and the body

What is the microbiome?;

The human microbiome is the collection of microorganisms (bacteria, fungi, viruses) that normally live on our body, mainly in the gut. The gut microbiome constitutes a dynamic ecosystem that actively participates in many vital bodily functions, such as digestion, the production of bioactive substances, and interaction with the immune system.

The balance of the microbiome is considered important for overall well-being, as it affects multiple bodily systems.

Where is it and what is it doing?;

The microbiota is mainly located:

• in the gut (mainly in the large intestine)
• but also in the mouth, skin, and other surfaces

Your role will include:

• Participation in food digestion
• production of metabolites (e.g. short-chain fatty acids)
• interaction with the immune system
• maintaining the balance of the intestinal environment

How do postbiotics relate

Postbiotics, such as bacterial lysatesLactobacillus, Streptococcus), they are not live microorganisms, but they do contain bioactive components which can interact with the intestinal environment.

Instead of “adding” bacteria, they work:
supportive of the microbial environment
through signalling mechanisms with the cells of the intestine

Studies show that they can affect the functional balance of the microbiome and communication between microbes and the host.

Where does this balance help?;

A balanced microbiome is linked to:

• Normal digestion
• good bowel function
• balanced interaction with the immune system
• Total internal balance of the organism

Maintaining this balance is a key element of the modern approach to well-being.

Conclusion

Postbiotics are a new generation of ingredients that:

• do not rely on live microorganisms
• interact with the organism's microbial environment
• integrated into a modern approach to daily support

Bibliography

• Valdes A.M. et al. (2018). The role of gut bacteria in nutrition and health. BMJ.
• Salminen S. et al. (2021). Postbiotics – definition and scope. Nature Reviews Gastroenterology & Hepatology.
• Aguilar-Toalá J.E. et al. (2018). Postbiotics: An evolving term. Trends in Food Science & Technology.
• Thursby E., Juge N. (2017). Introduction to the human gut microbiota. Biochemical Journal.

What do postbiotics do

The Bacterial lysates They have shown that they can:

Immune support

• “train the immune system
• They help the body's defence.

Bacterial lysates (postbiotics), such as those derived from strains Lactobacillus and Streptococcus, These represent a modern approach to supporting the body's natural defences. Although they do not contain live microorganisms, they retain structural components (e.g. cell walls, peptides, metabolites) that interact with immune system cells. They have been shown to influence cytokine production and contribute to the regulation of the immune response.

Their action is often described as «training» the immune system, as they enhance the body's ability to respond to external factors in a balanced way. Furthermore, they appear to support the natural defence mechanisms, contributing to the maintenance of immunological homeostasis.

On a modern lifestyle level, postbiotics are a sophisticated choice for daily support, offering a scientifically substantiated approach without the use of live microorganisms.

Bibliography

• Aguilar-Toalá J.E. et al. (2018). Postbiotics: An evolving term within the functional foods field. Trends in Food Science & Technology.
• Salminen S. et al. (2021). Postbiotics – definition and scope. Nature Reviews Gastroenterology & Hepatology.
• Taverniti V., Guglielmetti S. (2011). The immunomodulatory properties of probiotic microorganisms beyond live cells. Microbial Cell Factories.
• Wegh C.A.M. et al. (2019). Postbiotics and their potential applications in early life nutrition. International Journal of Molecular Sciences.

Strengthening of intestinal barrier

• help gut health
• support the microbiome

The intestinal barrier is a key component of overall health, protecting the body from harmful agents and regulating the passage of substances. Bacterial lysates have been shown to help maintain the integrity of the intestinal epithelium, enhancing the function of tight junctions and mucin production.

In parallel, postbiotics appear to support the balance of the intestinal microenvironment, indirectly positively influencing the composition of the microbiome. This leads to better functional stability of the gut and overall support for digestive well-being.

In a modern context, where diet and stress affect gut health, postbiotics are an innovative approach to maintaining the balance and functionality of the digestive system.

Bibliography

• Bermudez-Brito M. et al. (2012). Probiotic mechanisms of action. Annals of Nutrition & Metabolism.
• Valdes A.M. et al. (2018). The role of gut bacteria in nutrition and health. BMJ.
• Aguilar-Toalá J.E. et al. (2021). Postbiotics: What else?. Journal of Food Science.
• Żółkiewicz J. et al. (2020). Postbiotics—a step beyond pre- and probiotics. Nutrients.

Anti-inflammatory action

• They can reduce inflammatory responses

Low-grade chronic inflammation is a significant factor affecting general health. Postbiotics have attracted the interest of the scientific community due to their ability to influence inflammatory mechanisms.

Studies show that bacterial lysates can contribute to the regulation of pro-inflammatory and anti-inflammatory factor production, helping to maintain the body's balance. At the same time, they appear to enhance cellular defence mechanisms and support the body's adaptation to environmental challenges.

This makes postbiotics a modern choice for those seeking holistic wellness support, based on scientific data and advanced nutritional solutions.

Bibliography

• Cicenia A. et al. (2014). Postbiotic activities of lactobacilli-derived factors. Journal of Clinical Gastroenterology.
• Tsilingiri K., Rescigno M. (2013). Postbiotics: What else?. Beneficial Microbes.
• Żółkiewicz J. et al. (2020). Postbiotics—a step beyond pre- and probiotics. Nutrients.
• Aguilar-Toalá J.E. et al. (2018). Postbiotics: An evolving term. Trends in Food Science & Technology.

Stability and security

• more stable than probiotics
• No refrigeration required

Postbiotics stand out due to their stability, as they do not contain live microorganisms. This makes them more resistant to environmental conditions, such as temperature and storage, and facilitates their use in modern supplement forms.

Furthermore, they present a high safety profile, as the risk associated with the use of live bacteria is reduced. The absence of live microorganisms means that special storage conditions, such as refrigeration, are not required, while their bioactivity is maintained.

This makes them particularly suitable for consumers looking for practical and reliable solutions, combining scientific evidence with ease of use.

Bibliography

• Salminen S. et al. (2021). Postbiotics – definition and scope. Nature Reviews Gastroenterology & Hepatology.
• Aguilar-Toalá J.E. et al. (2018). Postbiotics: An evolving term. Trends in Food Science & Technology.
• Wegh C.A.M. et al. (2019). Postbiotics in health and disease. International Journal of Molecular Sciences.
• Taverniti V., Guglielmetti S. (2011). Heat-killed probiotics and immunomodulation. Microbial Cell Factories.